Our Story

About

HINEC Lab

Founded at Yonsei University, HINEC pioneers higher-order neural connectivity analysis. We develop computational tools that reveal brain organization invisible to traditional pairwise methods.

2024
Founded
4
Core Researchers
54
Publications
12.4K
Citations
Mission

Decoding the Brain Beyond Pairwise Connections

Traditional neuroscience analyzes brain connectivity as pairwise links between regions. But the brain operates through higher-order interactions: synergistic assemblies where three, four, or more regions encode information collectively.

HINEC develops the mathematical frameworks, computational tools, and machine learning architectures needed to detect, quantify, and decode these higher-order neural interactions at scale.

Vision

A Future Where Brain Topology Guides Medicine

We envision a future where topological biomarkers from higher-order connectivity analysis become standard clinical tools for diagnosing and monitoring neurological disorders.

5
Critical lifespan transitions discovered
3.7x
Improvement in disorder classification
400x
Computational speedup achieved
14
Novel clinical biomarkers identified
Principles

Our Values

Rigor

Every claim is backed by rigorous statistical testing, reproducible code, and open datasets. We hold ourselves to the highest scientific standards.

Impact

Our work aims to improve human lives. From clinical biomarkers to BCI technology, we translate theory into tools that matter.

Openness

We believe in open science. Our code, data, and methods are publicly available. Collaboration accelerates discovery.

Innovation

We challenge the paradigm of pairwise connectivity. Higher-order interactions demand new mathematics, new algorithms, new thinking.

People

The Team

Dr. Sehun Chun

Dr. Sehun Chun

Principal Investigator

Leading expert in topological data analysis and computational neuroscience. PhD in Applied Mathematics from MIT. Pioneer of persistent homology applications in brain connectivity.

Focus: Topological Data Analysis, Persistent Homology
28
Publications
22
h-index
Woosung Choi

Woosung Choi

Lead Research Scientist

Specialist in information theory and neural coding. Developed the O-information pipeline for higher-order interaction detection. Expert in synergy-redundancy decomposition.

Focus: Information Theory, O-Information
15
Publications
14
h-index
Taehyun Han

Taehyun Han

Deep Learning Architect

Creator of the DSSNN architecture for brain state classification. Expert in geometric deep learning on simplicial complexes and hypergraphs.

Focus: Geometric Deep Learning, DSSNN
12
Publications
11
h-index
Miras Koilybay

Miras Koilybay

Research Engineer

Specialist in GPU-accelerated computing and hypergraph signal processing. Built the HINEC-OI toolkit achieving 400x speedup over CPU implementations.

Focus: HPC, Hypergraph Signal Processing
8
Publications
7
h-index
Growth

Lab Analytics

Interactive visualizations of our growth and impact. Hover for details.

Funding Sources (% allocation)
45.0
NRF
30.0
NIH
18.0
EU
12.0
Industry
8.0
Internal
History

Milestones

2026

Nature Neuroscience Publication

Topological phase transitions paper accepted. Identified 5 critical lifespan stages in brain connectivity.

2025 Q4

NeurIPS Best Paper Honorable Mention

DSSNN architecture receives recognition for SOTA brain state classification results.

2025 Q3

HINEC-OI v2.0 Released

Open-source toolkit achieves 400x GPU speedup. Downloaded by 200+ research labs worldwide.

2025 Q2

NIH R01 Grant Awarded

$2.4M grant for clinical translation of topological biomarkers in Alzheimer's disease.

2025 Q1

Science Publication

Synergistic neural assemblies paper published, establishing higher-order interactions as primary substrate of cognition.

2024

HINEC Lab Founded

Lab established at Yonsei University with 4 founding members and seed funding from NRF Korea.